TNF and inflammation: Deng et al. [49] found that miR-590-3p, an exosome secreted by M2 cell macrophages, could alleviate intestinal inflammation by inhibiting LPS-induced release of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 from FHC cells through modulation of the LATS1/YAP/ β-Catenin axis.