Second, four out of nine signature proteins downregulated in patients with AD and food allergies (i.e., Krt77, Asah1, Ggh, Cat) were significantly decreased in the RoraEKO epidermis vs. the control (Figure 3C,D), indicating RORα could be critical for maintaining the expression levels of these important genes [43]. The gene discussed is GGH; the disease is food allergy.