ICAM1 and myocardial infarction: Interestingly, heart tissue from rats with acute myocardial infarction supported by VA-ECMO showed increased myocardial ICAM-1 levels compared to healthy controls [33], while in rabbits with prolonged hemorrhagic shock, VA-ECMO resuscitation reduced the immunohistochemical staining of ICAM-1 expression in intestines compared to fluid resuscitation, but the levels were significantly higher here compared to healthy controls [36].