Furthermore, the increase in lipid mediator levels may also promote the progression of neurological disorders by controlling the oligomerization of aggregate pathogenic proteins (β-amyloid (Aβ), α-synuclein (α-Syn), mutated huntingtin (Htt), and mutated Cu/Zn-superoxide dismutase1 (SOD1)) associated with the pathogenesis of each disease. Here, HTT is linked to nervous system disorder.