However, in another study, insulin levels and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) were elevated in patients with SCH in comparison to euthyroids, with TSH levels correlating directly with insulin and HOMA-IR, wherein free-T3 levels correlated negatively and strongly with insulin and moderately with HOMA-IR [40]. The gene discussed is INS; the disease is spindle cell hemangioma.