The breakdown of the BBB is associated with several neuroimmunological diseases, including multiple sclerosis (MS), neuromyelitis optica (NMO), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), autoimmune encephalitis (AE), and neuropsychiatric systemic lupus erythematosus (NPSLE) [2,10]. This evidence concerns the gene OMG and multiple sclerosis.