The addition of YKL40 promotes the proliferation of HEK293 (human embryonic kidney cells) and U373 (human glioblastoma cells) cells through Erk phosphorylation [44] and the proliferation and migration of SW480 and COLO205 cells (colorectal cancer cells) via the NF-κB pathway [45]. Here, NFKB1 is linked to colorectal cancer.