PLK3 and cancer: In the P-phase endometrial samples, genes related to cell adhesion (GRHL2) and positive regulation of cell migration (ELP3) were significantly upregulated in the pEMS group compared with the pCT group, while genes related to angiogenesis (SRPX2), the MAPK signaling pathway (DUSP1 and DUSP5), proteoglycans in cancer (PLAUR), negative regulation of apoptotic process (PLK3), and positive regulation of endothelial cell proliferation (NR4A1) were significantly downregulated in the pEMS group compared with the pCT group (Figure 7a).