When these genes were cross-referenced with genes known to be regulated by the miRNA-221, which is believed to be a marker for viral HCC development, we detected nine genes of interest: ANGPTL2, BBC3, BMF, MMP1, MYBL1, NTF-3, PLXNC1, RNF44, and SUN2. The gene discussed is BBC3; the disease is hepatocellular carcinoma.