Macrophages and neutrophils were enriched in bronchoalveolar lavage in severe compared to moderate COVID-19 [202], and single-cell RNA sequencing revealed an upregulation of the G-protein coupled receptor GPR183, initiating migration of macrophages towards a gradient of the oxysterol 7α,25-dihydroxycholesterol in COVID-19 patients [203,204]. This evidence concerns the gene GPR183 and COVID-19.