Variants of T-ALL with inv(7) (p15q34;TRB::TLX1) in combination with delCDKN2AB/9p21 and cases of translocation of TRB::TLX1 in combination with delCDKN2AB/9p21 and del TP53/17p13 are also described [18]. The gene discussed is THRB; the disease is acute lymphoblastic leukemia.