Several recurrent translocations like t(1;7)(p32;q34)/TRB::TAL1, t(7;9)(q34;q32)/TRB::TAL2, t(7;12)(q34;p12) TRB::LMO3, inversions inv(7)(p15q34) and translocations t(7;7)(p15;q34) TRB::HOXA10, as well as t(6;7)(q23;q34) [TRB::MYB] with overexpression of MYB have been reported in T-ALL [2,15]. The gene discussed is LMO3; the disease is acute lymphoblastic leukemia.