PUF60 and ovarian cancer: We investigated the expression of these genes in a subset of ovarian cancer cell lines, and the same pattern was observed, where RAD21 CNV is strongly associated with PUF60 and LY6E (Pearson 0.76, Spearman 0.79, p-value 1.56 × 10−140 and Pearson 0.74, Spearman 0.76, p-value 7.80 × 10−14, respectively) (Supplementary Figure S2).