TNF and type 2 diabetes mellitus: Elevated levels of CRP, interleukin (IL)-1, IL-6, C-X-C motif chemokine ligand 10 (CXCL10), tumor necrosis factor (TNF)-α, IL-12 (p70), IL-13, and IL-17A are associated with an increased risk of T2DM and diabetic neuropathy [6,11].