CDNF and Parkinson disease: Indeed, CDNF has manifested neuroprotective and neurorestorative effects in animal models of PD [25,26,27,28,29,30,31,32,33,34], Huntington’s disease [35], amyotrophic lateral sclerosis [16], peripheral nerve damage [20,21,36], and ischemic [37] and hemorrhagic stroke [24].