TLR4 and endometritis: On the other hand, it was reported that the peroxisome proliferator-activated receptor γ (PPARγ) inhibits pro-inflammatory cytokines (TNFα, IL-1β, and IL-6), TLR4, and NF-κB, relieving LPS-induced endometritis in pig endometrial epithelial cells (EECs) [80].