IL6 and COVID-19: Furthermore, in addition to an effective antiviral activity, these in vitro studies also highlighted lactoferrin’s ability to downregulate IL-6 production and affect iron homeostasis, thus supporting its potential role in controlling COVID-19-associated cytokine storm and iron overload, the latter being two critical features of ARDS, one of the most severe COVID-19 complications [4,10,15,68,70,71].