A total of 11 unique protein-coding genes posterior probability (PP) of H4 > 0.70 finally remained, including GSTM3 for senile cataract, WARS1, C3, IGFBP7, and PILRA for AMD, ECI1, LCT, and NPTXR for glaucoma, EFEMP1 for myopia, and SIRPG and SIGLEC14 for DR. Here, IGFBP7 is linked to age-related macular degeneration.