For example, plasma-protein-coding gene AGER was identified in AMD (FDR.p = 4.79 × 10−2) and DR (FDR.p = 2.32 × 10−63), brain-protein-coding gene DDAH2 was identified in senile cataract (FDR.p = 4.02 × 10−2) and DR (FDR.p = 1.16 × 10−16), and brain-protein-coding gene PLEKHA1 was identified in senile cataract (FDR.p = 7.45 × 10−3) and AMD (FDR.p = 4.40 × 10−58). This evidence concerns the gene AGER and Age-related cataract.