Bayo et al. revealed that the migration of BMDCs towards the HCC milieu is conditioned on the production of IL-8/CXCL8, growth-regulated oncogene (GRO)/CXCL 1-2-3, and monocyte chemotactic protein-1 (MCP-1)/CCL2 by the HCC microenvironment; however, there was no impact on HCC aggressiveness. The gene discussed is CXCL1; the disease is hepatocellular carcinoma.