Previous studies have shown that overexpression of GADD45A can cause G2/M cell cycle arrest and reduce proliferation in T24 bladder cancer cells, as well as induce G0/G1 and G2/M phase arrest in EBV+ B lymphoma cells through the activation of the p38 MAPK/TAp73/GADD45A axis [24]. This evidence concerns the gene GADD45A and urinary bladder carcinoma.