A 2.5-year-old boy was diagnosed with metastasized high-risk neuroblastoma in our center (primary tumor: bilateral abdominal sympathetic chains with infiltration of left kidney; metastases: osteomedullar lesions, lymph nodes; genetics: diploid MYCN, ALK R.1275Q mutation with allele frequency in tumor: 21.4%, blood plasma: 40.1%, bone marrow plasma: 40.5%). Here, ALK is linked to neoplasm.