β-Thromboglobulin (β-TG) [16], P-selectin [17], and platelet factor 4 (PF4) [18] have been previously reported as biomarkers of platelet activation; however, their actual specificity for the diagnosis of arterial thrombosis and the evaluation of antiplatelet therapy efficacy are not high, and they have limited use in the clinical laboratory setting. The gene discussed is PF4; the disease is Arterial thrombosis.