- Lowers BP, fluid volume, albuminuria, and left ventricular hypertrophy in rats with nephrectomized kidneys that have been given a salty diet- Enhances fecal sodium excretion, decreases urine sodium excretion and intestinal sodium uptake, and significantly decreases SBP in rats- Causes natriuresis and substantially lowers hypertension in Ang II-infused, high-salt-fed rats. This evidence concerns the gene AGT and Hypertension.