Furthermore, exogenous APL peptides (APL-13 and -36) have prevented endotoxin- and ventilation-induced ALI by reducing inflammation, acute ACB dysfunction, and TGFβ1-mediated endothelial-to-mesenchymal cell-related fibrosis [25,26,29,55,56,57,58,59]. The gene discussed is TGFB1; the disease is acute respiratory distress syndrome.