To date, histopathological findings of affected nerves in CNTN1-AN have revealed axonal loss and fiber degeneration in the absence of onion bulbs, as well as scant thinly myelinated fibers and prominent sub-perineurial edema, in contrast to biopsies of patients with CIDP [48,88,89]. Here, CNTN1 is linked to chronic inflammatory demyelinating polyradiculoneuropathy.