It is interesting that in the group of youngest children, HOMA-IR was additionally strongly correlated with BMI (r = 0.5), ALT (r = 0.4), DBP (r = 0.6), and FM (r = 0.5), presumably due to a greater genetic predisposition for the development of metabolic complications associated with obesity [24]. The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.