Patients receiving the combined therapy demonstrated lower levels of indexes related to cardiac function, including NT-proBNP and cardiac troponin I, as well as lower levels of renal function, including serum cystatin C, serum creatinine, and neutrophil gelatinase-associated lipocalin, indicating that the addition of low-dose dopamine may improve cardiac and renal function in HF. Here, LCN2 is linked to hydrops fetalis.