The compound 2-[(6-nitro-2-benzothiazolyl)amino]-2-oxoethyl4-[2-(N,N-dimethylamino)ethyl] piperazine-1 carbodithioate (BPCT, Figure 3i) was evaluated as an AChE inhibitor in an AD model induced with streptozotocin (STZ). Here, ACHE is linked to Alzheimer disease.