Among the dominant DEMs, there are 45 dominant DEMs such as pterostilbene, L-ascorbic acid, and riboflavin, etc. Among them, pterostilbene is a phytoalexin for polyphenol compounds, which was originally isolated from the heartwood of red sandalwood and has potential health benefits in inflammatory skin diseases, light protection, cancer prevention and treatment, insulin sensitivity, blood glucose and blood lipid levels, cardiovascular diseases, aging, memory, and cognition [47]. This evidence concerns the gene INS and inflammatory skin disease.