Oncogenic miRs such as miR-21, miR-25, and miR-27a have been reported to be downregulated by EGCG in MCF-7 (breast cancer), MM1.s (multiple myeloma), and 22Rv1 xenograft (prostate tumor) [71,72,73], resulting in decreased expression of vascular endothelial growth factor (VEGF) and IL-6 and increased expression of p53, p21, and caspase-3. Here, VEGFA is linked to plasma cell myeloma.