ADSL and bacterial infectious disease: AMPs represent a promising alternative to conventional antibiotics, and their efficacy against bacterial infections can be maximized when encapsulated within lipid‐based nanoparticles.[6, 16, 17, 33, 34, 43] This paper investigates how the active peptide‐to‐lipid ratio of LL‐37 and GMO and, ultimately, their structural properties in solution impact their antimicrobial activity.