Based on the bulk RNA-seq data analysis, 13 DE-NRGs were screened out between MDS and health controls, including TNFRSF1A, PPID, PLA2G4A, MLKL, IL1A, TNFSF10, FAS, JAK2, STAT1, STAT3, IRF9, USP21, BAX. This evidence concerns the gene JAK2 and myelodysplastic syndrome.