Nonetheless, as compared to the ARC group, the USG and POAG groups exhibited notably elevated IL-6 (P = 0.001; P < 0.001), IL-8 (P < 0.001; P < 0.001), and MCP-1 (P < 0.001; P = 0.003) levels respectively. The gene discussed is CXCL8; the disease is open-angle glaucoma.