During the present study of IKZF2, HL was also associated with IKZF2 since monoallelic variants affecting ZFs 3 and/or 2, were described in ICHAD syndrome (Immunodysregulation, Craniofacial anomalies, Hearing impairment, Athelia and Developmental delay) (Mohajeri et al 2023). This evidence concerns the gene IKZF2 and hearing loss disorder.