NKX2-1 and Anxiety: We did not find any significant differences in the distance covered in an open field (Fig. 7A) or in the time spent in the open arms of the elevated plus maze (Fig. 7B) between Nkx2.1-Cre cHET and control littermates, in contrast to Syngap1+/− mice which displayed hyperactivity and reduced anxiety/higher risk-taking (Clement et al., 2012; Berryer et al., 2016).