SYNGAP1 and neurodevelopmental disorder: In summary, collectively our results, together with other findings (Francavilla et al., 2024), suggest that Syngap1 plays a role in PV interneuron development during a critical pre- or/and perinatal developmental window and adds to the growing evidence highlighting the contribution of cortical PV inhibitory interneurons to sensory and cognitive abnormalities in neurodevelopmental disorders.