Moreover, Erastin- or RSL3-induced cell death in PCa cells, regulated by HJURP, was significantly blocked by the ferroptosis inhibitors ferrostatin-1 and liproxstatin-1, but not by the apoptosis inhibitor Z-VAD-FMK, the necroptosis inhibitor necrosulfonamide, or the autophagy inhibitor 3-methyladenine (Fig. 1G and H, Supplementary Fig. S2C). Here, HJURP is linked to posterior cortical atrophy.