To understand the mechanism by which HJURP inhibits cell death induced by ferroptosis inducers, we determined the main factors involved in ferroptosis modulation [18], including Fe2+ levels, GSH levels, ROS production, and the protein expression of xCT−, ACSL4 and GPX4, in HJURP-knockout PCa cells. Here, SLC7A11 is linked to posterior cortical atrophy.