In addition, both HJURP and PRDX1 protein levels were negatively correlated with OS rates in PCa patients (Fig. 2F), and thus functioned as independent prognostic factors for OS (HJURP, HR = 2.75, 95 % CI = 1.07–7.04, P = 0.035; PRDX1, HR = 3.35, 95 % CI = 1.57–7.18, P = 0.002; Supplementary Table S3). This evidence concerns the gene PRDX1 and posterior cortical atrophy.