Public data (Human Protein Atlas proteinatlas.org [20]) showed that high expression of HSH2D correlates with a significantly lower 5-year survival rate in colorectal cancer patients (65 % for patients with low expression of HSH2D vs. 47 % for high expression; P= 9.5e-6) (Fig. 3B). The gene discussed is HSH2D; the disease is colorectal cancer.