The transcriptome analysis of BMDCs revealedthat treatment with cGAMPnps and DAMPs from Dox-treated 4T1 cellsled to significant alterations in genes related to blood vessel remodeling,as shown in Figure 3E. This finding prompted us to explore how STING activation by Dox-cGAMPnp@Gelmight influence tumor vascular remodeling. This evidence concerns the gene STING1 and neoplasm.