To gain insight into the mechanism by which the LRP1 β‐chain modulates apoptosis of HCC cells, we constructed a plasmid carrying a β∆‐chain coding sequence and observed similar changes in Bax and Bcl‐2 expression in β∆‐chain‐overexpressing cells (Figure 3b,c). The gene discussed is BCL2; the disease is hepatocellular carcinoma.