Low‐density lipoprotein receptor‐related protein‐1 (LRP1) is a multifunctional endocytic and cell signaling receptor containing an extracellular α‐chain and a membrane‐anchored cytoplasmic β‐chain.[4] In addition to its important role in lipid and glucose metabolism, LRP1 has been implicated in tumor cell proliferation, angiogenesis, invasion, and migration.[5] Bian et al. Here, LRP1 is linked to neoplasm.