BCL2 and hepatocellular carcinoma: Instead, we found obvious activation of the NF‐κB/Bcl‐2 anti‐apoptotic signaling pathway in parallel with enhanced tumorigenicity in LRP1‐knockdown HCC cells, which was attributed to increased O‐GlcNAcylation of NF‐κB p65 and the consequent upregulation of its anti‐apoptotic activity.