LCN2 and chronic kidney disease: Post renal embolization at eight months of age, renal blood flow was no longer impaired (Fig S1, a) and the kidney showed significant increase in fibrosis (amount of Picrosirius Red staining) in the areas surrounding the microspheres (Fig. 1c–e) as well as a significant rise in urinary NGAL in the CKD animals (Fig. 1f).