Co-treatment with KPA also decreased the expression of genes (Figure 7I,J), regulating the progression of fibrosis (e.g., COL6A3, AEBP1, SPARC, TNC, LAMB1, BGN) and hepatocellular carcinoma (e.g., COL4A1, COL4A2, TUFT1, VCAN, NID1). This evidence concerns the gene NID1 and hepatocellular carcinoma.