On the other hand, GAS6, as a ligand of the TAM subfamily of receptor tyrosine kinases (Tyro3, Axl, and MerTK), can exert two contrasting effects on liver diseases: in acute liver injury, the GAS6/TAM axis promotes tissue repair and reduces inflammation, contributing to the wound healing response; conversely, in chronic liver diseases, it stimulates inflammation and tissue fibrosis [250]. This evidence concerns the gene GAS6 and liver disorder.