CSF2 and obesity due to melanocortin 4 receptor deficiency: On the other hand, obesity was associated with a smaller concentration of FGF (−51% and −68% for visObese (−) vs. visLean and visObese (+) vs. visLean, p < 0.05; Figure 3B) and GM-CSF in the medium (on average by −0.43 pg/mL, p < 0.05; Figure 3D).