As observed in Figure 6A, the photoactivation of the FONPs[Cp6] in the HCT116 CRC cells induced a significant increase in the percentage of activated caspases-3/7 in a time-dependent manner, with 86.6% compared to 6.1% in the light control, at 48 h post-illumination. The gene discussed is CASP3; the disease is colorectal carcinoma.