NOTCH1 and cancer: The results showed that somatic mutations were detected in coding sequence (CDS) regions of only 8 of 21 targeted cancer-related genes, TP53, KMT2D, CREBBP, KRAS, PTEN, NOTCH1, MYD88, and CARD11 (Tables 1 and 2; Table S3 summarized in Fig. 2).