It is known that type 2 cytokines produced by Th2 cells can drive B cell differentiation and eosinophil recruitment, both immunopathogenic drivers of allergic and atopic diseases, while Th17 cytokines including IL-6 and IL-17 are critical mediators for several autoimmune diseases including rheumatoid arthritis and psoriasis (23, 33–35). This evidence concerns the gene IL17A and rheumatoid arthritis.