Additional loci/genes that have been identified in multiple GWAS include furin paired basic amino acid cleaving enzyme (FURIN) and a cluster of genes on chromosome 9, across which significant variants in LD reside, including suppressor of cancer cell invasion (SCAI), phosphatase 6 catalytic subunit gene (PPP6C), and Rab9 effector protein with Kelch motifs (RABEPK). The gene discussed is FURIN; the disease is cancer.