As expected, the hydrocarbonated metabolism was altered in the PCOS groups, in which levels of insulin and homeostasis model assessment of insulin resistance (HOMA‐IR) were increased (p < 0.05), as well as other surrogate markers of IR, such as complement factor c3 (C3c) and retinol‐binding protein 4 (RBP4) (p < 0.001). This evidence concerns the gene RBP4 and polycystic ovary syndrome.