When adjusted for age, gout duration, height, weight, BMI, SBP, DBP, HbA1c, FPG, fasting insulin, FFA, SUA, SCr, serum ionized Ca and serum P, the significant association between serum ionized Mg levels and the risk of bone erosion persisted in Q2 (p<0.01), Q3 (p<0.01) and Q4 (P<0.001) with OR (95%CI) of 0.520 (0.340, 0.797), 0.533 (0.345, 0.824) and 0.411 (0.265, 0.636). Here, INS is linked to gout.