CDKN2A and pancreatic intraductal papillary-mucinous neoplasm: Furthermore, commonly mutated driver genes identified in precursor lesions (PanIN, IPMN and mucinous cystic neoplasm, MCN) include, besides KRAS, p16/CDKN2A, GNAS and RNF43, depending on the type of precursor lesion [28].