APOE and atherosclerosis: As flaxseed oil exerted anti-atherosclerosis effect against high-fat diet-induced ApoE−/− mice (55), the BAs included LCA, ACA, GCA, and TCA were negatively correlated with seven bacteria (Intestinimonas, Bilophila, Anaerotruncus, Oscillibacter, Negativibacillus, etc.), and alloLCA, isoLCA, 7-ketolca, β-UDCA, CDCA, HDCA, and α-MCA were positively correlated with these bacteria.