On the other hand, for flaxseed oil revealed anti-atherosclerosis action on high-fat diet-induced ApoE−/− mice (58), the acetic acid and propionic acid in feces were negatively correlated with seven bacteria (Intestinimonas, Oscillibacter, Lachnoclostridium, Bilophila, Enterorhabdus, etc.). This evidence concerns the gene APOE and atherosclerosis.